| abstract |
PURPOSE: To obtain the titled compound useful as a synthetic intermediate of pharmaceuticals, agricultural chemicals, dyes, functional polymers, organic electrically conductive materials, etc., in high yield, by reacting an aryl halide with a cyanoacetic acid ester in the presence of a small amount of a specific catalyst. n CONSTITUTION: The objective compound of formula II or III can be prepared by reacting the aryl halide of formula Ar-Xm or formula I (Ar if aryl or arylene; X is halogen; Y is O, S or alkylene; m is 1 or 2; n is 0 or 1) with the cyanic acid ester of formula CNCH 2 COOR 1 (R 1 is alkyl, aralkyl or aryl) in nitrogen gas stream in the presence of a catalayst and basic condensation agent, in a solvent at 20W140°C. The reaction is carried out in the presence of a catalyst consisting of a bivalent palladium complex of formula Q a Pd(II)X* b (Q is nitrile, π-allyl, 1,5-diene, etc.; X* b is halogen; a and b are 1 or 2) and ligand compound of formura IV (Z is P, As, Sb, etc.; R 3 WR 5 are alkyl, alkenyl, aryl, etc.). n COPYRIGHT: (C)1986,JPO&Japio |