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filingDate 1983-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5a0873926327bc54495832d590418d2
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publicationDate 1985-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S6084213-A
titleOfInvention Sustained release type anti-inflammatory and analgesic pharmaceutical
abstract PURPOSE: A sustained release type anti-inflammatory and analgesic pharmaceutical, containing "Indomethacin" in collagen or gelatin, and capable of remarkably enhancing the effectiveness thereof. n CONSTITUTION: A sustained release type anti-inflammatory and analgesic pharmaceutical obtained by adding "Indomethacin" of the formula which is a nonsteroidal antirheumatic agent to a solution containing a biodegradable carrier selected from collagen and gelatin, stirring the resultant mixture, concentrating and if necessary spray-drying or freeze-drying the resultant mixture. Atherocollagen which is obtained by treating collagen with an enzyme, e.g. pepsin, removing the heteropeptide part, and reducing the antigenecity can be used to enhance further the safety thereof. n COPYRIGHT: (C)1985,JPO&Japio
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