http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6078962-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 |
| filingDate | 1983-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5cf7dea762d62651ee7622e4ad4192c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4637953de4fc8fd2a509946b9fc404c |
| publicationDate | 1985-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6078962-A |
| titleOfInvention | Production of prostaglandin d1 |
| abstract | PURPOSE: To obtain a PGD 1 useful as a medicine easily in high yield, by protecting the hydroxyl group at the 9-position of a specific PGF 1 α with a group capable of forming an acetal bond, and subjecting the protected PGF 1 α to the selective removal of the protecting groups, oxidation, removal of the protecting group and hydrolytic reaction. n CONSTITUTION: The hydroxyl group at the 9-position in a PG(prostaglandin)F 1 α of formula I [R 11 is 1W10C alkyl or tri(1W7C) hydrocarbon silyl; R 2 and R 3 are H, substituted or unsubstituted 1W10C alkyl, etc.; R 31 is tri(1W7C) hydrocarbon silyl; R 41 is a group capable of forming an acetal bond with the oxygen atom of the hydroxyl group] is protected with the group capable of forming the acetal bond with the oxygen atom of the hydroxyl group at the 9-position thereof to give a PGF 1 α, which is then subjected to selective removal of the protecting groups, oxidation and hydrolytic reaction to afford the aimed PGD 1 of formula II(R 1 is H or 1W10C alkyl; R 4 and R 5 are H, etc.). n EFFECT: Separation of isomers of cubic configuration is not necessary. n COPYRIGHT: (C)1985,JPO&Japio |
| priorityDate | 1983-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.