http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6078596-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01c1e0bc0628f76dea731cda5a666ca1 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 1983-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c006a95a31a2cc3e42cc320eacfd228 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8043c3660f369a10a36415466c0a9d84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e67ed96872fde8ce70877f404f529d4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c6769f8defd4fc938e1522235776f29 |
| publicationDate | 1985-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6078596-A |
| titleOfInvention | Preparation of optically active oxazolidine derivative by immobilized enzyme |
| abstract | PURPOSE: To stabilize an enzyme and to enable the repeating use of it, by immobilizing an enzyme to hydrolyze a specific oxazolidine to a hydrophobic carrier. n CONSTITUTION: An esterase capable of asymmetrically hydrolyzing (A) a racemic modification of 3-alkyl-substituted-5-acyloxymethyloxazolidin-2-one shown by the formula I (R 1 is 1W4C alkyl group; R 2 is alkyl group) is immobilized to a hydrophilic carrier, and the prepared immobilized enzyme is packed into a column. The compound A is loaded onto the column, and water or a buffer solution is made to flow into it, to carry out asymmetric hydrolysis. An optically active hydrophilic 3-alkyl-substituted-5-hydromethyloxazolidin-2-one shown by the formula II prepared by the reaction is eluted with water or a buffer solution. Then, an optically active hydrophobic 3-alkyl-substituted-5-acyloxymethyoxazolidin-2- one shown by the formula III which is adsorbed on the carrier of the immobilized enzyme in the column, supported, and is not a substrate of the asymmetric hydrolysis, is diluted with an organic solvent. n COPYRIGHT: (C)1985,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H01309696-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0534957-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5032523-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5187094-A |
| priorityDate | 1983-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.