http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S606690-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b9036c33bbe3f4ea428655b76200f7c |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 |
| filingDate | 1983-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf62d20243388a0108b64956bb30881e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63f7943821b33ca827c07ff584c2a76f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6652ee429abf1ef4da3fe8601792544a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19fbadb3059dc933f9d6fd90eff2445b |
| publicationDate | 1985-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S606690-A |
| titleOfInvention | Novel (1) benzepino (3,4-b) pyridine derivative |
| abstract | NEW MATERIAL:A compound shown by the formula I {R<1> is H, (halogenated) alkyl, alkoxy, or halogen; X is O, or S; R<2> is group shown by the formula V[Y is (substituted) amino, or (substituted) hetero ring; Z is H, alkyl, or amino; n is 1-3], or group shown by the formula VI (m is 0-2)}, and its acid addition salt. EXAMPLE:5-[2-(Diethylamino)ethyl]amino-5,11-dihydro [1] benzoxepino [3,4-b] pyridine. USE:An antitumor agent. PREPARATION:A compound shown by the formula II is reduced with a metal hydride complex compound such as lithium aluminum hydride, etc. to give a compound shown by the formula III. It is reacted with a halogenating agent such as thionyl chloride, etc. to give a compound (acid addition salt) shown by the formula IV (Q is halogen), which is then reacted with a compound shown by the formula Z'-NH-(CH2)n-Y(Z' is H, or 1-5C alkyl) or a compound shown by the formula VII. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0655674-B1 |
| priorityDate | 1983-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.