| abstract |
PURPOSE: To produce an aromatic iodine compound convertible to fine chemicals, economically, in high yield and selectivity, by reacting an aromatic hydrocarbon with I 2 in a solvent using nitrogen dioxide as an inexpensive and easily handleable oxidation agent. n CONSTITUTION: An aromatic hydrocarbon such as diphenyl ether, acetanilide, 1,2-methylenedioxybenzene, benzofuran, o-xylene, etc. is made to react with I 2 in a solvent such as dichloromethane preferably at 10W150°C introducing nitrogen dioxide optionally carried by an inert gas such as N 2 gas, etc. into the system to obtain the objective compound such as 4,4'-diiododiphenyl ether, 4-iodo-acetanilide, etc. n EFFECT: The nitrogen monoxide produced by the reaction is oxidized with air to nitrogen dioxide, and reused for the reaction. The separation and purification of the product can be carried out easily because of high selectivity. The reaction condition is extremely mild, and there is little danger of the corrosion of the apparatus, etc. n COPYRIGHT: (C)1985,JPO&Japio |