abstract |
PURPOSE: To provide novel titled compound having excellent physiological activity, especially anticancer and antifungus activity, constituted by structural unit of specific formula. n CONSTITUTION: The objective substituted phenylureide propylpolysilsesquioxane constituted by structural unit of formula [X is sulfamoyl or bis(β-chloroethyl) amino]. Said polysilsesquioxane can be prepared, for example, by the hydrolysis of γ-(substituted phenylureide) propyltrialkoxysilane followed by condensation, or by the reaction between γ-aminopropylpolysilsesquioxane and substituted phenylisocyanate. n USE: Anticancer drug, antifungus agent. n COPYRIGHT: (C)1985,JPO&Japio |