http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6042331-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_692dc75829481c48c017b52f352e2bad |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-42 |
filingDate | 1983-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c0f52ff7ea05b540a70b9c5044528c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11362c187ef6698a115bc990f49bf1e1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_707ffc6e6fe22a64e20400b15a3b698a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e59885b498c763b0b0e2fbb37dd26f14 |
publicationDate | 1985-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S6042331-A |
titleOfInvention | Production of polysaccharide n9gi |
abstract | PURPOSE: To obtain a polysaccharide N9GI having low toxicity and useful as an antineoplastic agent, by decoloring and purifying the colored polysaccharide N9GI obtained from the hot-water extract of the bark of Melia azadirachta, with a hypohalous acid salt without lowering the pharmacological activity of the polysaccharide. n CONSTITUTION: The polysaccharide N9GI obtained from the hot-water extract of the bark of Melia azadirachta has brown color originated from the bark, and cannot be decolored even by activated carbon treatment. The polysaccharide is dissolved in water, added with an aqueous solution of a hypohalous acid salt in an amount of preferably 0.2W1%, and stirred at room temperature for 2W15min. The reaction liquid is treated with a dialyzing membrane, etc. to remove excess hypohalous acid salt, and freeze-dried to obtain white polysaccharide N9GI. The hypohalous acid salt is preferably the hypochlorite, hypobromite or hypoiodite of Na or K. The pharmacological acitivity remains unchanged by the decoloring treatment. n COPYRIGHT: (C)1985,JPO&Japio |
priorityDate | 1983-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.