http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6041664-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_660c8e47c6f16717455c549a11e97d85 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4406 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 |
| filingDate | 1983-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_085170c802423074b80c2dc9c8feee1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e5c10ab9b4c2f90d4d7cea284f70221 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c2f5e63d429b0282fd2a84c81eb03544 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13823d589da08a0a92b6d0fba5aaa241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc8dcb8e63acb639ef4b2ee5b6130828 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d879a6d98b282754a7dceac70625a48 |
| publicationDate | 1985-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6041664-A |
| titleOfInvention | Benzoic acid derivative |
| abstract | NEW MATERIAL:A benzoic acid derivative shown by the formula I (X is group shown by the formula II, formula III, or formula IV) and its salt. n EXAMPLE: p-(3-Pyridylmethoxymethyl)benzoate hydrochloride. n USE: An inhibitor against an enzyme synthesizing thromboxane A 2 . Useful for remedying various kinds of disease such as thrombosis, myocardial infarction, diabetic vascular complication, asthma, etc. resulting from thromboxane A 2 . n PREPARATION: Nicotinic aldehyde is condensed with malonic acid to give a reaction product, which is converted in HCl-containing methanol by heating to give a compound shown by the formula V. This compound is hydrogenated in a solvent in the presence of Pd/C catalyst at normal pressure, which is subjected to Grignard reaction with p-diethoxymethylphenylmagnesium bromide, and treated with a mineral acid to give a compound(novel compound) shown by the formula VI, which is oxidized with an oxidizing agent in a mixed solvent to give a compound shown by the formula I where X is a group shown by the formula II. n COPYRIGHT: (C)1985,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5061716-A |
| priorityDate | 1983-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.