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filingDate 1983-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c05fb11c2f6997ef40e636cadd1bb6fd
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publicationDate 1985-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S604132-A
titleOfInvention Novel alpha-amylase inhibitory substance
abstract NEW MATERIAL:α-Amylase inhibitory substance WAI-65[soluble in water, dilute salt solution, insoluble in methanol, etc., molecular weight: 24,000 (gel filtration); 11 peptides are obtained by digestion of trypsin and have their N terminal groups shown by the table I ; amino acid composition shown by the table II; ratio of necessary amount of the substance of inhibit 50wt% human salivary gland amylase per unit to that to inhibit 50wt% pancreas amylase per unit (1:500)W(1:600) in the inhibitoy curve of the substance to the human salivary gland amylase and the pancreas amylase; an amount to inhibit 50wt% salivary gland amylase per international unit is 72.4μg.]. n USE: An α-amylase inhibitoy substance. n PREPARATION: Wheat or wheat flour is stirred in 3W10 times as much water preferably purified water as raw material by weight for 1W5hr at room temperature. The suprnatant liquid is collected by operations such as centrifugation, decantation, filtration, etc. It is heated in vacuum or under normal pressure, and optionally centrifuged agin, to give α-amylase inhibitoy substance WAI-65. n COPYRIGHT: (C)1985,JPO&Japio
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