http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6036410-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e1bf06f55de84b78abc9a057807f7eb |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-205 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-18 |
filingDate | 1983-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6479fa1bb5cf9701cee3f15ec946ff0a |
publicationDate | 1985-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S6036410-A |
titleOfInvention | Preparation of donor of biodegradable drug |
abstract | PURPOSE: To provide the titled donor capable of releasing the drug in a living body under controlled condition, by dissolving chitin in a solvent, contacting the obtained dope with a coagulating liquid to obtain swollen chitin, impregnating the swollen chitin with a drug-containing solution, and drying the product. n CONSTITUTION: Chitin (poly-N-acetyl-D-glucosamine) is dissolved in a solvent (e.g. trichloroacetic acid), and the obtained dope is charged in a pressure tank and extruded with a gear pump, etc. through a sepcific die into a coagulating liquid (e.g. water, alcohol, ketone, etc.) to obtain a swollen product having the form of rod, ring, sheet, etc. The product is impregnated with a solution containing a drug (e.g. proteinous drug, anti-infective, carcinostatic agent, remedy for ophthalmic diseases, etc.), and dried to obtain the objective donor. When the donor is brought ino contact with a body fluid, it releases the drug slowly over a lont time into the body fluid, and finally the donor itself also disappears. The releasing period can be adjusted. n COPYRIGHT: (C)1985,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0194838-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04138169-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61268616-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62129226-A |
priorityDate | 1983-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.