http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6036410-A

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36
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filingDate 1983-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6479fa1bb5cf9701cee3f15ec946ff0a
publicationDate 1985-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S6036410-A
titleOfInvention Preparation of donor of biodegradable drug
abstract PURPOSE: To provide the titled donor capable of releasing the drug in a living body under controlled condition, by dissolving chitin in a solvent, contacting the obtained dope with a coagulating liquid to obtain swollen chitin, impregnating the swollen chitin with a drug-containing solution, and drying the product. n CONSTITUTION: Chitin (poly-N-acetyl-D-glucosamine) is dissolved in a solvent (e.g. trichloroacetic acid), and the obtained dope is charged in a pressure tank and extruded with a gear pump, etc. through a sepcific die into a coagulating liquid (e.g. water, alcohol, ketone, etc.) to obtain a swollen product having the form of rod, ring, sheet, etc. The product is impregnated with a solution containing a drug (e.g. proteinous drug, anti-infective, carcinostatic agent, remedy for ophthalmic diseases, etc.), and dried to obtain the objective donor. When the donor is brought ino contact with a body fluid, it releases the drug slowly over a lont time into the body fluid, and finally the donor itself also disappears. The releasing period can be adjusted. n COPYRIGHT: (C)1985,JPO&Japio
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priorityDate 1983-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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