http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6034960-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97ddd4d1d0ebc8a7d2c8e7d214d08cf3 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-48 |
filingDate | 1983-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_997913a18c6d154585045fc315e1a80b |
publicationDate | 1985-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S6034960-A |
titleOfInvention | Synthetic intermediate for mevalonic acid and production of labeled mevalonic acid therefrom |
abstract | NEW MATERIAL:The synthetic intermediate of mevalonic acid of formula I (R 1 is H, methoxyethoxymethyl, ethoxyethyl, benzyl of benzyloxymethyl; R 2 is H, 1W4C alkyl or alkali metal salt; X is deuterium or tritium). n EXAMPLE: Z-Ethyl-2-deutero-2,3-epoxy-3-methyl-5-ethoxyethyloxypentanoate. n USE: Intermediate for the production of labeled mevalonic acid. The acid can be produced from an inexpensive raw material in high yield, by the use of the novel intermediate. n PREPARATION: For example, the alcohol group of 3-butyn-1-o1 is protected, and the alcohol is treated with a chlorocarbonic acid ester in the presence of a strong base. The treated product is made to react with copper iodide and methyl lithium, treated with labeling water, and epoxidized to obtain one of the compound of formula I . The obtained compound of formula I is reduced and converted to an alcohol to obtain the mevalonic acid derivative of formula II. n COPYRIGHT: (C)1985,JPO&Japio |
priorityDate | 1983-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.