http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S60239500-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e1bf06f55de84b78abc9a057807f7eb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9bcf92061ce8f6ff3e220f21317036b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d75d1a4caed60a9316608ed9c231546c |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 |
filingDate | 1984-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e784fb3c8335e6d42b61844e6777294 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_992f32e92ffa5acff998946e833ea033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e15c9199e4efbbcefdc101e92fcc92ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df7381dcbe8f039caa110ec19969c8b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eea72dd28f0162190d4e0d6b0bb136e4 |
publicationDate | 1985-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S60239500-A |
titleOfInvention | Preparation of tyrosyl oligopeptide having radioactive iodine imparted thereto |
abstract | PURPOSE: To obtain a tyrosyl oligopeptide in high yield with high reproducibility and carry out easily the subsequent radioactive iodination process, by reacting tyrosine with an oligopeptide at a selected charging molar ratio. n CONSTITUTION: (C) An oligopeptide, e.g. synthetic human C-peptide, is reacted with (D) tyrosine in a molar amount within 0.01W10mol range based on one mol component (C) in the presence of (A) tyrosyl-tRNA synthetase (an enzyme catalyzing the reaction; tyrosine+ATP+tRNA→tyrosyl-tRNA+AMP+pyrophosphoric acid, optimally obtained from thermostable bacteria, e.g. Bacillus thermophilus) and (B) adenosine triphosphate, preferably at 1:1W1:100 molar ratio between the components (A) and (B) to give a tyrosyl oligopeptide, which is then iodinated with radioactive iodine ( 125 I) to afford the aimed substance. n COPYRIGHT: (C)1985,JPO&Japio |
priorityDate | 1984-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.