http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S60239425-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
| filingDate | 1984-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28ec0baa04f0d4d95eba93c150527959 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_660ffcb5cbe15ea0bf83081f747645e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f87e960f2d2fcbf05734e87a710cb92 |
| publicationDate | 1985-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S60239425-A |
| titleOfInvention | Solid carrier for control of lipid metabolism |
| abstract | PURPOSE: To provide the titled carrier produced by a specific fused cell, having immobilized monoclonal antibody, and useful for the adsorption and removal of cholesterol. n CONSTITUTION: An antibody-producing cell existing in the spleen or the lymph node of an animal immunized with an apolipoprotein B (e.g. apo B100, apo B48, etc.) is fused with the myeloma cell of the same or different kind of animal, and a fused cell producing a specific monoclonal antibody is separated by cloning. The cell is cultured in a proper medium or in the body of an animal to effect the immobilization of the monoclonal antibody which reacts specifically with the apolipoprotein B in the human plasma but does not react with the other apolipoproteins. A solid carrier for the control of lipid metabolism and useful for the adsorption and removal of the very low-density lipoprotein (VLDL) and/ or low-density lipoprotein (LDL) in blood plasma can be prepared by the above process. It can be used effectively for the remedy of hyperlipemia, etc. n COPYRIGHT: (C)1985,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-5561484-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-8912390-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0257778-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0311094-A2 |
| priorityDate | 1984-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.