| abstract |
NEW MATERIAL:A compound of formula I (R 1 , R 2 , R 3 are H, protecting groups for hydroxyls) and its salt. n EXAMPLE: 4-Cyano-1-β-D-ribofuranosylimodazolium-5-oleate. n USE: A carcinostatic agent. n PREPARATION: The deprotection of a compound of formula II (R is protecting group for hydroxyl) such as 4-carbamoyl-1-(2,3,5-tri-O-acetyl)-β-D-ribofuranosyl)- imidazolium-5-oleate is carried out using phosphorus oxychloride, preferably by about 2mol amount to the compound for 2W3hr to give the compound of completely or partially deprotection. n COPYRIGHT: (C)1985,JPO&Japio |