http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S60188398-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb4ee28d43b5e8d4a3c5141fa9bcfeb0 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
filingDate | 1984-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a0ed056872066151bb9590056738abe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf1d827e8c8b0b63559643e4eefd000b |
publicationDate | 1985-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S60188398-A |
titleOfInvention | Production of 6beta-fluoro-delta1,4-pregnadiene derivative |
abstract | PURPOSE: To produce the titled fluorine-containing steroid compound useful as an anti-inflammatory agent, in high yield, by reacting an alkali metal salt of an organic acid with fluorine gas, reacting the product with Δ 3.5 -pregnadiene derivative, and separating the objective product from the reaction product. n CONSTITUTION: An organic acid alkali metal salt (e.g. CH 3 COONa) is made to react with fluorine gas (usually diluted to ≤20mol% with an inert gas such as N 2 ) preferably in a chlorofluorocarbon solvent at about -75°C. The obtained reaction mixture is made to react with a Δ 3.5 -pregnadiene derivative, and the objective compound is separated from the product by column chromatography, high-performance liquid chromatography, etc. n COPYRIGHT: (C)1985,JPO&Japio |
priorityDate | 1984-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 16.