| abstract |
PURPOSE:The titled anti-inflammatory that contains a combination of guaiazulene or its sodium sulfonate salt with a specific surface active agent, thus showing enhanced anti-inflammatory effect without side-effects. CONSTITUTION:The objective agent is composed of guaiazulene or sodium guaiazulenesulfonate and surface active agents selected from chloroacetyl pyridinium, benzethonium chloride, benzalkonium chloride, sodium laurylsulfonate, chlorhexidine, and chlorhexidine salts. The amounts of both components are 0.03-1wt% in the anti-inflammatory component (calculated as guaiazulene) and 0.01-1.0wt% in the surfactant respectively, preferably at a weight ratio of 1:(0.5-5) the anti- inflammatory to the surfactant. |