http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S60169482-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_630b360599ea5cf4b5bcbc0c6c0a3e2d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-00 |
| filingDate | 1984-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8db865828813248c67261e2bed32b8f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_40376b083f396850316faf51b0b66880 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27ea6499028f3b0231492765a2bb23fb |
| publicationDate | 1985-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S60169482-A |
| titleOfInvention | Preparation of aminated phthalide-isoquinoline |
| abstract | PURPOSE: To obtain industrially and advantageously the titled compound useful as a medicine, by reducing a specific nitro compound which is an epimeric mixture into an amino compound and epimerizing the resultant amino compound in the presence of an alkali at a specific temperature. n CONSTITUTION: A 1RS-3'RS epimer of an amino compound expressed by formula II(R 3 WR 6 are the same as R 3 'WR 6 ' except nitro) is obtained from a mixture of the 1RS-3'RS epimer with a 1RS-3'RS epimer of a nitro compound expressed by formula I (R 1 and R 2 are H or lower alkoxyl, at least one of R 3 'WR 6 ' is nitro, and the rest is H or lower alkoxyl; R 7 is lower alkyl). In the process, the compound expressed by formula I is previously reduced to give the compound expressed by formula II, which is epimerized in the presence of an alkali at 20W 100°C to afford the aimed aminated phthalide-isoquinoline expressed by formula II. n COPYRIGHT: (C)1985,JPO&Japio |
| priorityDate | 1984-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.