abstract |
PURPOSE: To produce the titled compound useful as an intermediate for agricultural chemicals, pharmaceuticals, dyes, ultraviolet absorbers, etc., in high purity and yield, by reacting a halogenobenzophenone compound with methanol under alkaline condition at a specific temperature. n CONSTITUTION: A methoxybenzophenone compound such as 2,2',4,4'-tetramethoxybenzophenone is produced by reacting a halogenobenzophenone compound such as 2,2',4,4'-tetrachlorobenzophenone with methanol in the presence of an alkali metal compound such as potassium hydroxide in a solvent (preferably dimethyl sulfoxide) at 50W100°C, preferably 60W80°C. The alkali metal compound is preferably added to the reaction system in two or more divided portions. n EFFECT: The production of by-product can be minimized, and the reaction is completed in a relatively short time. n COPYRIGHT: (C)1985,JPO&Japio |