| abstract |
PURPOSE: The titled pharmaceutical for external use, obtained by incorporating an ultraviolet light absorber and if necessary an antioxidant in a pharmaceutical for the external use containing "Ketoprofen", and capable of specifically and remarkably suppressing the photodecomposition of the "Ketoprofen". n CONSTITUTION: A pharmaceutical for external use obtained by incorporating 0.01W5wt%, preferably 0.1W1wt%, based on the total amount of the pharmaceutical, ultraviolet light absorber and if necessary 0.01W5wt%, preferably 0.05W 1wt%, based on the total amount of the pharmaceutical, antioxidant, e.g. ascorbic acid, stearic acid ester or tocopherol, in a pharmaceutical for the external use, e.g. an ointment, gel, fomentation or aerosol, containing "Ketoprofen". A p- aminobenzoic acid derivative, anthranilic acid derivative, benzophenone derivative, salicylic acid derivative, amino acid based compound, etc. may be used as the ultraviolet light absorber, and the benzophenone derivative is particularly preferred. n COPYRIGHT: (C)1985,JPO&Japio |