| abstract |
NEW MATERIAL:A compound expressed by formula I [R is CH 3 , C 2 H 5 , formula II(R 1 is H, Cl, Br, CH 3 OCH 3 or NO 2 ) formula III or formula IV (R 2 , R 3 and R 4 are the same or different H, CH 3 , OCH 3 , NO 2 or OH)]. n EXAMPLE: β-Bromophenacyl β-(6-isocyano-3,7-dioxatricyclo[4.1.0.0 2 , 4 ]heptan-4-yl) acrylate. n USE: An antimicrobial agent having improved antimicrobial and antimycoplasma activity with low toxicity. n PREPARATION: A β-(6-isocyano-3,7-dioxatricyclo[4.1.0.0 2 , 4 ]heptan-4-yl)acrylic acid expressed by formula V is reacted with e.g. p-bromophenacyl bromide, in methylene chloride solvent in the presence of an organic base, e.g. triethylamine, at the boiling point or below. n COPYRIGHT: (C)1985,JPO&Japio |