http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S60149522-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_067bc5ace16106b2ed7bc6f1198d59ae |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-12 |
filingDate | 1984-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81d2a92514e74d9539a90f7d1d30fded |
publicationDate | 1985-08-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S60149522-A |
titleOfInvention | Immunoactivating agent |
abstract | PURPOSE: To provide an immunoactivating or immunoregulating agent containing a specific indole derivative such as 5-hydroxytryptamine (5-HT), etc. n CONSTITUTION: The objective agent contains the compound of formula I [R is group of formula II (Y is H or carboxyl; m is 1W3), -(CH 2 ) n -COOH (n is 1W3), -CH 2 -C(O)-COOH, group of formula III, or -CHO; X is H or OH] or its salt, as an active component. It has been found that the 5-HT of formula IV known as a nerve impulse transmission substance in living body and the 5-hydroxytryptophan (5-HTP) of formula V known as a precursor to produce 5-HT by the action of 5-hydroxylase are effective to promote the damaging activity of lymphocyte T-cell to carcinoma cell in test tube, and that although 5-HT and 5- HTP have no activity to damage carcinoma cell, however, the compounds exhibit antitumor activity in the living body when administered to a cancer- carrying host. n COPYRIGHT: (C)1985,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2597339-A1 |
priorityDate | 1984-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.