http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6011461-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 |
| filingDate | 1983-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc73a53703b5cdb6582ae13ea7614f2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a3e031c2c78c88ee6aed81c1b9b7b78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af077c7d9d9674b4ad64a0c88ceaed0f |
| publicationDate | 1985-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6011461-A |
| titleOfInvention | Production of 6-oxoprostaglandin e1 compound |
| abstract | PURPOSE: To produce the titled compound easily, from an easily available raw material, by adding an organic copper lithium compound to a 4-substituted-2- cyclopentenone compound by the conjugated addition reaction, reacting the product with nitroolefin, and converting the nitro group to oxo group. n CONSTITUTION: The 4-substituted-2-cyclopentenone compound of formula I [R 2 is tri(1W7C)hydrocarbon-substituted silyl, or forms acetal bond together with O of OH] is made to react with the organic copper lithium compound of formula II(R 3 is same as R 2 ; R 4 is H, methyl, ethyl, etc.; R 5 is 4W12C alkyl, etc.; Y is I, phenylthio, cyano, etc.) in an aprotic organic solvent by the conjugated addition reaction. The reaction product is made to react with the nitroolefin compound of formula III (R 1 is 1W12C alkyl, 2W10C cycloalkyl, etc.), the nitro group is converted to oxo group, and if necessary, the product is subjected to the deprotecting hydrolyzing and salt-forming reaction to obtain the objective compound of formula IV. n COPYRIGHT: (C)1985,JPO&Japio |
| priorityDate | 1983-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.