| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f4c2477bdea308bc9dec3feded37457 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-57 |
| filingDate |
1982-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e16be29c463fe9f0bc43b036d52fb698
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccc6dfd19f7658445caf6dc634e9b698
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f68d95fc9cac0247787fb994451e497b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73140a3261476751260a0b50d245bbe4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8984f73aac5685224c84f355340414f5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd46a4b4c97e26ccdbf8f077fc479988
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7340110e67c56638d7346444ceb5c530 |
| publicationDate |
1984-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-S5993084-A |
| titleOfInvention |
3-unsubstituted-3-cephem derivative, its preparation and antibacterial agent composed thereof |
| abstract |
NEW MATERIAL:The compound of formula I (R 1 is H or methoxy; R 2 is H or OH) and its non-toxic salt. n EXAMPLE: 7β-[ D-2-( 6,7-Dihydroxychromone-3-carboxamido )-2-( 4-hydroxyphenyl)- acetamido]-3-cephem-4-carboxylic acid. n USE: An antibacterial agent effective to Gram-negative bacteria such as Pseudomonas aeruginosa. Some of the compound of formula I are low-toxic. n PROCESS: The compound of formula I can be prepared by reacting the compound of formula II or its salt with the compound of formula III or its reactive derivative in a solvent such as acetone in the presence of a silylation agent. The reaction is carried out by the conventional method of amidation reaction, e.g. in the presence of a condensation agent such as N,N'-dicyclohexylcarbodiimide. n COPYRIGHT: (C)1984,JPO&Japio |
| priorityDate |
1982-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |