http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5976076-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382ccfc2ebebcaee15aa7cda4cee86bc |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D279-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5415 |
| filingDate | 1982-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8be4d680d9d2735dc1c9be2a2ff834c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64bf4428d69a997e1caabf4a0f5289b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_215e4604782f6be036dc59e854e1e19f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63c36bd41049c89936a457c1687263a4 |
| publicationDate | 1984-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5976076-A |
| titleOfInvention | Benzothiazine derivative |
| abstract | NEW MATERIAL:A benzothiazine derivative shown by the formula I (R 1 is lower alkyl; X 1 and X 2 are halogen) and its salt. n EXAMPLE: 7,8-Dichloro-2,3-dihydro-3-methyl-4H-benzothiazine. n USE: An intermediate for synthesizing a pyrido[1,2,3-de][1,4]benzothiazine derivative useful as a remedy for diseases caused by various kinds of pathogenic microorganisms of men, animals, fishes, etc., surgical germicide for medical tools, and disinfectant. Showing improved antibacterial activity against Gram- positive and Gram-negative bacteria, having low toxicity and weak side effect. n PROCESS: A compound shown by the formula II (X 3 is halogen) is nitrated to give a compound shown by the formula III, which is reacted with an alkali metal sulfide so that it is dimerized to give a compound shown by the formula IV. This compound is then reduced with iron, etc. to give a compound shown by the formula V, which is reacted with a compound shown by the formula VI (X=X 3 ) in the presence of a dehydrohalogenating agent, further reduced with NaBH 4 , etc. to give a compound shown by the formula I . n COPYRIGHT: (C)1984,JPO&Japio |
| priorityDate | 1982-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.