http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5953464-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 |
| filingDate | 1982-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61190ed228f5328b4e0906a06913c082 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4637953de4fc8fd2a509946b9fc404c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5cf7dea762d62651ee7622e4ad4192c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc73a53703b5cdb6582ae13ea7614f2c |
| publicationDate | 1984-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5953464-A |
| titleOfInvention | Novel preparation of prostaglandin e and f |
| abstract | PURPOSE: To prepare the titled compound useful as an odynegoga, easily in high yield, by the selective deoxidization reaction of easily synthesizable 7-thiobenzoyloxyprostaglandin compound, and if necessary, subjecting the product to the removal of the protecting group and/or the hydrolysis. n CONSTITUTION: The compound of formula II (R 1 is H, 1W10C alkyl, etc.; R 3 and R 4 are H, OH, etc.) can be prepared by the selective deoxidization reaction of 7-thiobenzoyloxyprostaglandin compound of formula I [R 11 is 1W10C alkyl or tri(1W7C)hydrocarbon-silyl; R 2 and R 5 are H, (substituted) 1W10C alkyl, or (substituted) cycloalkyl; R 31 and R 41 are H or protected OH; A is carbonyl or hydroxymethylene; B is -CH=CH- or -C≡C-; the linkage represented by a solid line is combination with a dotted line is a single or double bond] with tri-n- butyltin hydride, etc. If necessary, the product is subjected to the removal of the protecting group and/or hydrolysis, etc. The prostaglandin E compound or F compound can be prepared by this process economically and easily. n COPYRIGHT: (C)1984,JPO&Japio |
| priorityDate | 1982-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.