http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5933258-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2de3beee83d9c19278da409b72c777a8 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C403-20 |
filingDate | 1982-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_934b5507d895ea200465b24625558be5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_156db00e2d809bd00983d9dfed3f70f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28985950949b9cbd5253459d17b060d2 |
publicationDate | 1984-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S5933258-A |
titleOfInvention | Leukotriene b4 analogous compound, its preparation, and remedy containing it as active ingredient |
abstract | NEW MATERIAL:A compound shown by the formula I [R 1 is H, or 1W4C alkyl; R 2 is 1W8C alkylene; R 3 is H, 1W15C alkyl, or CH 2 -A-R 4 (A is cis-vinylene, or acetylene; R 4 is 1W12C alkyl); double bond between C 10 -C 11 shows E]. n EXAMPLE: ( 5RS )-6,7-Dihydro-5, 8-methano- 13,14,15,16,17,18,19,20 -octanol-leukotriene B 4 . n USE: An antiphlogistic and an antiallergic. Having an antagonism on leukotriene B 4 . n PROCESS: An aldehyde compound shown by the formula II (R 1a is 1W4C alkyl) is reacted with an allenylboric acid or allenylborate shown by the formula III(R 5 is H, or 1W4C alkyl) in an inert organic solvent at -78°CW room temperature, and, if necessary, saponified, to give a compound shown by the formula I . n COPYRIGHT: (C)1984,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5390869-A |
priorityDate | 1982-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.