http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5933227-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cfc033f059d282fcd915bc8be2ae53f |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-74 |
| filingDate | 1982-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5c5bc65959c997b9774032c1bc1726f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3164963e9c3b20a786709ca0137c68b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd8810658c6516fa618da5a4f4ef668e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85f362dbbe846741f825e533618acf9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0999b6337bab20129e24339be5c6e610 |
| publicationDate | 1984-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5933227-A |
| titleOfInvention | Antitumor substance rd-01, its preparation and pharmaceutical preparation containing the same |
| abstract | NEW MATERIAL:The thermally denaturated deoxyribonucleic acid RD-01 having antitumor activity developed by thermal denaturation, and its salt. The sodium salt of the substance has the following physical and chemical properties: appearance, white powder; melting point, no distinct melting point; elementary analysis, C 26.18-31.31%, H 4.02-4.98%, N 12.11-13.89%, P 8.13-9.18%, Na 3.02-4.28%; molecular weight, 30,000-1,000,000; solubility, soluble in water, insoluble in ethanol, methanol, ether and acetone; base composition (%), guanine 33.4, adenine 17.2, cytosine 32.5, thymine 16.9; effect of enzymatic treatment, loses antitumor activity with deoxyribonuclease I but keeps the activity with ribonuclease T2; etc. USE:An antitumor agent exhibiting antitumor activity via the immune reaction of the host. PROCESS:The disintegrated cell of bacteria belonging to Propionibacterium genus is centrifuged, and the resultant nucleic acid fraction is heated at 80-120 deg.C. |
| priorityDate | 1982-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.