http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S592686-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_afd115dec46c157d3739020ebd4d866b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y111-02002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-44 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-08 |
| filingDate | 1982-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14691db03eab0df672b57f9be7890e4e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c28ece987b4fb7ff53db863b9e66abac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c11865668661cbc4d7b42e4e52b4d878 |
| publicationDate | 1984-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S592686-A |
| titleOfInvention | Powder pharmaceutical preparation of myeloperoxidase |
| abstract | PURPOSE: A powder pharmaceutical preparation for suppressing reduction in activity with time during lyophilization and storage period, having increased solubility, obtained by adding citric acid (citrate) to myeloperoxidase. n CONSTITUTION: Myeloperoxidase is blended with citric acid or its salt (e.g., trisodium citrate, etc.) in an amount sufficient for its stability, to give a powder pharmaceutical preparation. A drug composition consisting essentially of myeloperoxidase shows a tendency to be unstable to lyophilization. When lyophilization is carried out, it is observed that myeloperoxidase activity is reduced or it decreases with time. When citric acid (citrate) is added to myeloperoxidase, reduction in myeloperoxidase activity during lyophilization and lowering in activity with time during storage period are suppressed, and the solubility of pharmaceutical preparation of myeloperoxidase is also raised. n COPYRIGHT: (C)1984,JPO&Japio |
| priorityDate | 1982-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.