| abstract |
NEW MATERIAL:A compound shown by the formula I (R is H, or acyl). n EXAMPLE: 1'-[[[(2-Chloroethyl)nitrosoamino]carbonyl]amino]-1'-deoxysucrose. n USE: An antileukemia, and antitumor agent. Having extremely low side effect such as atrophia action on the spleen, etc. n PREPARATION: A sucrose ureido derivative shown by the formula II is reacted with a nitrosating agent (e.g., alkali metal nitrite, nitrogen trioxide, etc.) in a solvent such as usually acetone, methanol, etc. preferably at -10W30°C. n COPYRIGHT: (C)1984,JPO&Japio |