http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S59216886-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6fc963308ccf64eb331ec81340aa56e2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-397 |
| filingDate | 1983-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74cd89e5ed17486aab620c68eec8deb1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c242044cacc1b3ac802915dc7a35be93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21f431e8807bb9fdfef1fbe7b7195f6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f423032a091e38835c7b5ee01425663d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b92d2e2d917c997091cb0ac50c08c451 |
| publicationDate | 1984-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S59216886-A |
| titleOfInvention | Carbapenem derivative |
| abstract | NEW MATERIAL:A compound of formula I (R is H, methyl) and its salt. n EXAMPLE: ( 3RS,4SR )-{3-[( 1RS )-Fluoroethyl]-2-oxozethidin-4yl}acetic acid benzyl ester. n USE: Antibacterial: it is used as an acetive ingredient for antibacterial preparations for prevention and treatment of gram-positive and -negative bacteria. The preparation therefrom is applied to bacterial diseases in men and mammarian animals. n PREPARATION: A compound of formula II (Z 1 is easily releasable carboxyl- protecting group) is fluorinated, the protecting group Z is eliminated, then a malonic acid derivative is allowed to react with the product. The reaction product is diazotized, ring closed, further allowed to react with phosphoryl halide to give a compound of formula VIII (Z 2 is Z 1 ; Y is alkyl). Then, the compound is allowed to react with a compound of formula XII (Z 3 , Z 4 are Z 1 ) to form a compound of formula IX, which is subjected to hydrogenolysis to form the compound of formula I . n COPYRIGHT: (C)1984,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S62192356-A |
| priorityDate | 1983-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.