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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-34
filingDate 1982-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e4a91e988a0496b00db7a5093f66c43
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publicationDate 1984-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S5921395-A
titleOfInvention Novel antibiotic indisocin, its n-methyl derivative, and its preparation
abstract NEW MATERIAL:Antibiotic indisocin and its N-methyl derivative having the following physical and chemical properties. Molecular formula: C 13 H 9 ClN 2 O 3 . Specific rotatory power [α] 25 D=+20±5° (C 0.03, methanol). Infrared absorption spectrum measured in CCl 4 solution shown by the figure. Solubility: soluble in methanol, acetone, ethyl acetate, chloroform, benzene, etc., slightly soluble in water. Color reaction: positive in Rydon Smith reaction, sulfuric acid, iodine, and cameleon reactions, negative in ninhydrin and TTC (2,3,5-triphenyltetrazolium) chloride reactions. n USE: An antibacterial agent having high antibacterial activity against Gram-positive and Gram-negative bacteria. n PROCESS: A bacterium [e.g., Nocardia blackwellii MG-323 hF2(FERM-P 6606)] belonging to the genus Nocardia, capable of producing antibiotic indisocin, is inoculated into a nutritive medium, cultivated at 4.5W8.0pH at 25W35°C, indisocin is collected from the culture, and subjected to N-methylation, if necessary. n COPYRIGHT: (C)1984,JPO&Japio
priorityDate 1982-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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