| abstract |
PURPOSE: To produce a sphingolipid derivative, by reacting a sphingolipid with a compound having an alcoholic hydroxyl group. n CONSTITUTION: A sphingolipid expressed by formula I is reacted with a compound having an alcoholic hydroxyl group in the presence of phospholipase DM to produce the aimed sphingolipid expressed by formula II. In the formulas I and II, A represents formula III or IV [R represents 16W24C saturated or unsaturated aliphatic hydrocarbon group; B represents -(CH 2 ) 2 N(CH 3 ) 3 , -(CH 2 )NH 2 or -CH 2 CH(OH)CH 2 (OH)]. n COPYRIGHT: (C)1984,JPO&Japio |