| abstract |
PURPOSE: To obtain a sulfide by easy operation in a short time, by reducing a thioacetal with an amineborane in the presence of a Lewis acid. n CONSTITUTION: A thioacetal, e.g. hemithioacetal or dithioacetal, is reduced with an amineborane, e.g. pyridineborane or diemethylamineborane, in the presence of a Lewis acid, e.g. aluminum chloride or zinc chloride, in an aprotic solvent, e.g. methylene chloride or tetrahydrofuran, to give the aimed sulfide. The hemithioacetal is generally unstable and cannot be ofter easily isolated. Therefore, after reacting a carbonyl compound with a thiol, the reaction mixture is preferably reduced directly with the amineborane in the presence of the Lewis acid. n COPYRIGHT: (C)1984,JPO&Japio |