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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08
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filingDate 1983-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13823d589da08a0a92b6d0fba5aaa241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df5913d47086177f103774ab2aea19ed
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publicationDate 1984-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S59144762-A
titleOfInvention Pyrazole derivative
abstract NEW MATERIAL:The compound of formula I (when R is H, R 1 is 3,4-dichlorobenzyl, 4-methylbenzyl, 4-methoxybenzyl or 3-trifluoromethylbenzyl; and when R is CH 3 , R 1 is 4-chlorobenzyl or 3,4-dichlorobenzyl). n EXAMPLE: 1-(3,4-Dichlorobenzyl)-3,4-dimethyl-5-methoxypyrazole. n USE: An antiallergic agent. n PREPARATION: When R is CH 3 , the objective compound can be prepared by (1) reacting ethyl 2-methylacetoacetate with the corresponding substituted benzylhydrazine compound in a solvent at room temperature in the presence of a mineral acid catalyst, and (2) methylating the resultant compound of formula II. When R is H, the objective compound is obtained by reacting dimethyl 3-oxoglutarate with a substituted benzylhydrazine compound, methylating the resultant compound of formula III, and subjecting the product to the hydrolysis and thermal decarbonation. n COPYRIGHT: (C)1984,JPO&Japio
priorityDate 1983-02-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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