http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S59134762-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6831b19bfc354357342f7c7da79fc162 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22 |
| filingDate | 1983-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88832db0e6e878a2c0b95c9b5139dc72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d30081e1194918696023f3f8aad5846e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17d0470dd3791a4b29044da8eb9ca51a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff5be7f61b421e19d51dd381c4f46f25 |
| publicationDate | 1984-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S59134762-A |
| titleOfInvention | 4-aminobutyric acid derivative and its preparation |
| abstract | NEW MATERIAL:The compound of formula I (R 1 is 1W4C straight-chain alkyl) and its salt. n EXAMPLE: D-4-[N-( 4-Acetlxy-3,3-dimethyl-2-hydroxy-n-butyryl )amino]-n-butyric acid. n USE: An agent for improving the cerebral metabolism and higher order cerebral function. It is converted to hopantenic acid in the body and gives high hopantenic acid concentration in the plasma and brain compared with the administration of calcium hopantenate. n PROCESS: The compound of formula I and its salt can be prepared either by the catalytic reduction of the novel 4-aminobutyric acid ester derivative of formula III(R 2 is group eliminable by catalytic reduction) followed by optional conversion to a salt, or by the reaction of the 4-amino-butyric acid derivative of formula III with a reactive derivative of the carboxylic acid of formula R 1 COOH. n COPYRIGHT: (C)1984,JPO&Japio |
| priorityDate | 1983-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.