http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S59122462-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 |
| filingDate | 1982-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc73a53703b5cdb6582ae13ea7614f2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75ab6139c4649f44c983d45e42a850e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a3e031c2c78c88ee6aed81c1b9b7b78 |
| publicationDate | 1984-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S59122462-A |
| titleOfInvention | Preparation of 5-thiaprostaglandin e1 compound |
| abstract | PURPOSE: To prepare the titled compound useful for pharmacological use, easily, in high yield, under mild reaction condition, by selectively reducing a 5-thia-Δ 7 - prostaglandin E 1 compound, and if necessary, carrying out the removal of protecting groups, etc. n CONSTITUTION: The 5-thiaprostaglandin E 1 compound of formula II is prepared by selectively reducing 5-thia-Δ 7 -prostaglandin E 1 compound of formula I [R 1 is H or 1W10C alkyl; R 2 is (substituted) 1W10C alkyl, etc.; R 3 and R 4 are H or protecting group; the wavy line between the double bond and S represents 7Z isomer, 7E isomer or their arbitrary mixture], and if necessary, subjecting the reduction product to the removal of the protecting groups and/or hydrolysis. The selective reduction can be carried out with a zinc reducing agent, organic tin hydride, or by the catalytic reduction with Raney-Ni catalyst. n COPYRIGHT: (C)1984,JPO&Japio |
| priorityDate | 1982-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.