| abstract |
PURPOSE: To obtain the titled substance useful as an intermediate for agricultural chemicals, drugs, etc. in high yield without problems of pollution, by reacting a furfural with Mg and a porpargyl halide in THF in the presence of a zinc halide as a catalyst, followed by hydrolysis. n CONSTITUTION: A furfural shown by the formula I (R 1 is H, CH 3 , or C 2 H 5 ) and a propargyl halide (e.g., propargyl chloride, 3-bromo-1-butene) are simultaneously treated with Mg in THF in the presence of a catalyst (of a zinc halide (e.g., zinc chloride) to give a compound shown by the formula II (R 2 is propargyl, or α-methylpropargyl). An amount of the propargyl halide used is 1.1W1.3 times the molar amount of the furfural, and an amount of Mg used is preferably ≥1.05 times the molar amount of it. The reaction temperature is 10W60°C. n EFFECT: Free from problems of recovery of mercury, as it replaces the existing method using a mercury catalyst. n COPYRIGHT: (C)1984,JPO&Japio |