| abstract |
NEW MATERIAL:26, 26, 26, 27, 27, 27-Hexafluoro-25-hydroxy-6, 19-epidioxy-vitamin D 3 . n USE: Remedy for leukemia. It has strong differentiation inducing activity to myelocytic leukemia cell and has little influence to the metabolism of calcium in the body. n PROCESS: 26,26,26,27,27,27-Hexafluoro-25-hydroxyvitamin D 3 is irradiated with a lamp emitting visible light, e.g. halogen lamp, tungsten lamp, etc., in the presence of a sensitizer such as Rose Bengal, Eosine, methylene blue, etc. in an inert solvent such as methanol, ethanol, etc. usually in oxygen gas stream to obtain the compound of the formula. n COPYRIGHT: (C)1984,JPO&Japio |