http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S59112962-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5575 |
| filingDate | 1982-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05c770f8fe49600c6a4da6a0e813be59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc73a53703b5cdb6582ae13ea7614f2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a3e031c2c78c88ee6aed81c1b9b7b78 |
| publicationDate | 1984-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S59112962-A |
| titleOfInvention | 5-thia-delta7-prostaglandin compound and its preparation |
| abstract | NEW MATERIAL:The compound of formula I [A is group of formula II (R 4 is H or protecting group) or -CH=CH- (cis); R 1 is H or 1W10C alkyl; R 2 is 1W10C alkyl or cycloalkyl which may be substituted; R 3 is H or protecting group; the notation of formula III is 7Z, 7E or their arbitrary mixture] or when R 1 is H, the salt of the acid. n EXAMPLE: 5-Thia-Δ 7 -prostaglandin E 1 . n USE: The compound is expected to have pharmacological activities such as carcinostatic, hypotensive, antiulcer, and antiviral activities, etc. It is useful also as a synthetic intermediate of novel 5-thiaprostaglandin E 1 having blood platelet coagulation inhibiting activity. n PROCESS: The compound of formula I wherein A is group of formula II can be prepared by reacting the 7-hydroxyprostaglandin compound of formula IV (R 31 and R 41 are protecting group) with a reactive derivative of an organic sulfonic acid in the presence of a basic compound at 0W30°C, treating the reaction product with a basic compound, and if necessary, subjecting the product to the removal of protecting groups, hydrolysis, and salt-forming reaction. n COPYRIGHT: (C)1984,JPO&Japio |
| priorityDate | 1982-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.