http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5795918-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a556ab1e1056ee33700f6dea5d511bb |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
filingDate | 1980-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_274a5df329187408c5161d35e59e6a24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_487bcec7c4eea20d4ec4039e435182f1 |
publicationDate | 1982-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S5795918-A |
titleOfInvention | Purification of immunoglobulin |
abstract | PURPOSE: To obtain high purity immunoglobulin useful as one of the plasma fraction preparations, by treating crude immunoglobulin obtained from extraction liquid of human placenta with chloroform, etc., and then with an adsorbent, and finally purifying with a cation exchange material. n CONSTITUTION: The extraction liquid of the human placenta is mixed with (NH 4 ) 2 SO 4 , and the precipitate is removed therefrom. The supernatant liquid is again mixed with (NH 4 ) 2 SO 4 , and the resultant crude immunoglobulin is treated with chloroform/ethanol mixture of with chloroform. The treated product is again treated with an adsorbent (e.g. acid clay, activated clay, kaolin, talc, etc.), and the product is purified with a cation exchange material (e,g. cation exchange resin, cation exchange cellulose, etc.) to obtain purified immunoglobulin. The extraction liquid of human placenta used as the starting material is obtained by cutting the placenta blood or placenta to small pueces, and extracting the blood component with physiological saline water. n EFFECT: Low denaturation of immunoglobulin, and high yield. n COPYRIGHT: (C)1982,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021020474-A1 |
priorityDate | 1980-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.