http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5795918-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
filingDate 1980-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_274a5df329187408c5161d35e59e6a24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_487bcec7c4eea20d4ec4039e435182f1
publicationDate 1982-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S5795918-A
titleOfInvention Purification of immunoglobulin
abstract PURPOSE: To obtain high purity immunoglobulin useful as one of the plasma fraction preparations, by treating crude immunoglobulin obtained from extraction liquid of human placenta with chloroform, etc., and then with an adsorbent, and finally purifying with a cation exchange material. n CONSTITUTION: The extraction liquid of the human placenta is mixed with (NH 4 ) 2 SO 4 , and the precipitate is removed therefrom. The supernatant liquid is again mixed with (NH 4 ) 2 SO 4 , and the resultant crude immunoglobulin is treated with chloroform/ethanol mixture of with chloroform. The treated product is again treated with an adsorbent (e.g. acid clay, activated clay, kaolin, talc, etc.), and the product is purified with a cation exchange material (e,g. cation exchange resin, cation exchange cellulose, etc.) to obtain purified immunoglobulin. The extraction liquid of human placenta used as the starting material is obtained by cutting the placenta blood or placenta to small pueces, and extracting the blood component with physiological saline water. n EFFECT: Low denaturation of immunoglobulin, and high yield. n COPYRIGHT: (C)1982,JPO&Japio
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021020474-A1
priorityDate 1980-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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