http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5793965-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6ae6f93cf0d2fcbb3ee0a112758fbd95 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-95 |
| filingDate | 1980-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c66f93b280da25418f3dfdbd0d4df63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8903526f57093a96681d036c7f12f4e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0f674aa19e76f049daf5304891c4ccb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0405c2ca2980d6e485fc80390b2625e7 |
| publicationDate | 1982-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5793965-A |
| titleOfInvention | Novel trimethoxyquinazoline derivative |
| abstract | NEW MATERIAL:The compound of formulaI[R is 1W5C lower alkyl, 3W7C cycloalkyl or (substituted) phenyl; X is O or S] or its acid addition salt. n EXAMPLE: 4-Amino-2-( 4-isopropylcarbamoyl-piperazin-1-yl )-6,7,8-trimethoxyquinazoline. n USE: A hypotensor. It has vasodilating activity based on α-adrenergic blocking and calcium antagonistoc activities. n PROCESS: The compound of formulaIis prepared by reacting 4-amino-2-piperazino-6,7,8-trimethoxyquinazoline of formula II (a novel compound) with an isocyanate or isothiocyanate of formula III in a solvent such as benzene at -20W +100°C. The compound of formula II can be prepared by the debenzylation of the compound of formula V obtained by the reaction of the compound of formula IV with benzylpiperazine. n COPYRIGHT: (C)1982,JPO&Japio |
| priorityDate | 1980-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.