http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5791971-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2de3beee83d9c19278da409b72c777a8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-935 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557 |
| filingDate | 1981-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1700bd35700d21321ce36e00f6ef050a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e9f62495efd850045a32082ba9ff20d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8879db67c16ec2974280b657ee860159 |
| publicationDate | 1982-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5791971-A |
| titleOfInvention | Preparation of prostaglandin analog compound |
| abstract | PURPOSE: To obtain the titled compound having a four-membered ring at the 16-position of the hydrocarbon side chain, by hydrolyzing a novel intermediate obtained from a specific aldehyde and phosphonic ester as starting materials under acidic conditions. n CONSTITUTION: A compound of formulaI[R 1 , R 2 and R 3 are H, 1W12C (substituted)alkyl or (substituted)aryl,; however, at least one is other than H; R 4 is 2-tetrahydropyranyl, 2-tetrahydrofuranyl or 1-ethoxyethyl; X is CH=CH or CH 2 CH 2 ; Z is O, etc.; formula XI is the configuration α or β is hydrolyzed under acidic conditions to give a compound of formula II. The novel compound of formulaIis obtained from an alicyclic aldehyde of formula IV (Ac is acetyl) and a phosphonic ester of formula V (R 5 is lower alkyl) as starting materials. The aimed compound of formula II is useful as an inhibitor against the gastric acid secretion without causing the hypotensive action or as an antiulcer agent. n COPYRIGHT: (C)1982,JPO&Japio |
| priorityDate | 1981-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.