http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5770893-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39ae96c0ecc22ff90ff986371a3cea0f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 |
| filingDate | 1980-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c03e48d4e737fba5bb5fba3905dea8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb755690f02d0d682791576ce4d1da10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f4033ad1a1b92f838732412ebfdea6df |
| publicationDate | 1982-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5770893-A |
| titleOfInvention | Preparation of cephalosporin derivative |
| abstract | PURPOSE: To obtain the titled compound useful as a synthetic intermediate for an antimicrobial agent or substance easily under mild conditions, by reducing a 3- cephem-4-carboxylic acid derivative or a salt thereof with a trivalent titanium compound. n CONSTITUTION: A 3-cephem-4-carboxylic acid derivative expressed by formulaI [R 1 is amino or acylamino; R 2 is halogen or nucleophilie compound residue, e.g. acyloxy; R 3 is carboxy or protected carboxyl or a salt thereof is reduced with a trivalent titanium compound, e.g. titanium chloride, to give a cepham compound expressed by formula II or a salt thereof and (or) a 3-cephem compound expressed by formula III or a salt thereof. The reaction is carried out frequently in the presence of a solvent, e.g. chloroform, usually under cooling in a nitrogen stream advantageously at a pH of 7W8. n COPYRIGHT: (C)1982,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4958018-A |
| priorityDate | 1980-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.