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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-147
filingDate 1980-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc52fc3992c8731b7e2e693b9132b65a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_980abb069168c530fda3e693dee0c7d1
publicationDate 1982-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S5764695-A
titleOfInvention Novel cephalotaxine derivative
abstract NEW MATERIAL:The compound of formulaI[R 1 is -(CH 2 ) i (i is integer 1W8) or -(CH 2 ) j -C 6 H 4 -(CH 2 ) k -j and k are O or integers 1W8); R 2 is -(CH 2 ) l -(l is O or integer 1W8) or -(CH 2 ) m -CHY(CH 2 ) n -(Y is H or ester group; m and n are O or integers 1W8); R 3 is H or iodine]. n EXAMPLE: 3-0-Succinylcephalotaxine(iodotyrosine methyl ester)amide. n USE: Labelling hapten for the radioimmunoassay of cephalotaxines. n PROCESS: For example, cephalotaxine of formula II is made to react with a dicarboxylic acid such as succinic anhydride to obtain 3-0-succsnylcephalotaxine, which is reacted with the compound of formula III, etc. in the presence of triethylamine, dicyclohexylcarbodiimide, etc. to afford the objective compound of formulaI. n COPYRIGHT: (C)1982,JPO&Japio
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Total number of triples: 32.