http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5762296-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_630b360599ea5cf4b5bcbc0c6c0a3e2d |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
filingDate | 1980-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d9e40ae2de6784c1ce22ee8fdcc4a72 |
publicationDate | 1982-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S5762296-A |
titleOfInvention | Preparation of 17alpha-hydroxyprogesterone derivative |
abstract | PURPOSE: To obtain the titled compound useful as an intermediate for a luteohormone, etc. industrially and advantageously, by reacting a specific 17β-cyano- 17α-hydroxyandrost-4-en-3-one, etc. with a methyl metallic compound, and hydrolyzing the resultant reaction product. n CONSTITUTION: (A) 17β-Cyano-17α-hydroxyandrost-4-en-3-one or 17β-cyano-17α- hydroxyandrosta-4,9 (11) -dien- 3-one in which the carbonyl group at the 3-position and the hydroxyl group at the 17α-position are protected is reacted with (B) a methyl metallic compound expressed by the formula CH 3 X (X is lithium atom or halomagnesium), e.g. methyl lithium, at -30W+100°C, and the resultant reaction product is then hydrolyzed to give the aimed compound. n COPYRIGHT: (C)1982,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4977255-A |
priorityDate | 1980-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.