http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5759888-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e86564cfd70ce948fc4d830ade6a3bd |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A24B3-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C11B9-00 |
| filingDate | 1980-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c090d6309a1b5214a2435e12373f9bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_975603562c35e926c32f03f3d892237a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74d87f832bf521b8b8fb9e8fc22b39b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_876a555e7e5138f1d4811794643fb57f |
| publicationDate | 1982-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5759888-A |
| titleOfInvention | Nornicotine derivative and tobacco flavor improver containing the same |
| abstract | NEW MATERIAL:A compound of formulaI(R is grup of formula II, formula III). n EXAMPLE: N'-(6-Hydroxyoctanoyl)nornicotine. n USE: Irritation inhibitor for tobacco, flavor improver showing great effect on reducing diagreeable taste and increasing good taste. n PREPARATION: Monomethyl adipate reacts with thionyl chloride to give adipic methyl ester chloride. The product is gradually added to a diethylcadmium solution and refluxed. Then, the reaction mixture is hydrolyzed with conc. sulfuric acid to form 6-oxo-octanoic methyl ester. The compound is made into the free acid by saponification with KOH-ethanol and neutralization with an acid to give the crystals of 6-oxo-octanoic acid. A solution of carbonyldiimidazole in dioxane is added to the acid and made to react with nornicotine to produce the compound of formulaIwhere R is group of formula II. n COPYRIGHT: (C)1982,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016196878-A1 |
| priorityDate | 1980-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.