| abstract |
NEW MATERIAL:A sulfonate drivative expressed by formulaI[R is phenyl which may have a substituent group (lower alkyl, lower alkoxyl, OH, carboxyl or halogen); R2 is 3W6C cyclic alkyl, 2W5C cyclic alkyl ether, etc.; m is an integer 0W3]. n EXAMPLE: 2-oxo-4-cyclohexyl-butyl-benzenesulfonate. n USE: An antithrombotic agent, andti-inflammatory agent and immunological regulator having esterase inhibitory and chymotrypsin inhibitory actions. n PROCESS: A compound expressed by formula II is reacted with a sulfonic acid compound expressed by formula III (Y is an integer 0W2) in a solvent, e.g. petroleum ether or ligroin, at -10W+60°C to give the compound expressed by formulaI. n COPYRIGHT: (C)1982,JPO&Japio |