| abstract |
PURPOSE: To provide a blood sugar level depressing agent containing a specific benzamide derivative as an active component. n CONSTITUTION: An agent containing the compound of formula [R 1 and R 2 are H, alkyl, (substituted) aralkyl, or (substituted) phenyl] as an active component. The compound of formula has excellent insulin biosynthesis promoting activity and blood sugar level depressing activity. It is effective at a dose of 0.lW100mg/kg for man, and maintains the activity for ≥24hr by the administration of 0.1W100mg/kg, once a day. The compound of formula can be prepared easily e.g. by reducing the corresponding m-nitrobenzoic acid amide by conventional method. n COPYRIGHT: (C)1982,JPO&Japio |