http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5718667-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5152bcb05bbc271001c0c3b31e8cc3c1 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-18 |
| filingDate | 1980-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9923149501c73db182080462ec86aabe |
| publicationDate | 1982-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5718667-A |
| titleOfInvention | Preparation of aporphine compound |
| abstract | PURPOSE: To obtain the titled substance useful as an analgesic, and anti-inflammatory agent, etc. in a short step in high yield, by reacting N-oxide of an isoquinoline derivative with cuprous chloride in a solvent. n CONSTITUTION: N-Oxide of an isoquinoline derivative expressed by formula I (R 1 is lower alkyl; n is 2) is reacted with cuprous chloride in a molar amount of 0.1W6 times that of the N-oxide of the isoquinoline derivative in a solvent at 0W80°C for 1W78hr to give a compound expressed by formula II (R 2 and R 3 are H or OH). A solvent having no direct influence on the reaction is usable, and preferably a lower alkyl alcohol, more preferably methanol, is used. n COPYRIGHT: (C)1982,JPO&Japio |
| priorityDate | 1980-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.